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If a new anti-cancer drug is found effective in initial tests with mice, what do researchers conclude?

If a new anti-cancer drug is found effective in initial tests with mice, what do researchers conclude?

The drug is effective in the mouse model; it must still be tested in humans.

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The effect of the drug on mice has no bearing on the effect of the drug on humans.

The mice have provided a positive control in this experiment that proves the drug is effective in humans.

If the drug was effective in a small proportion of mice, it will be effective in a small proportion of humans.

If the drug was effective in a large number of mice, it will therefore be effective in humans.

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